Tacrolimus CAS 104987-11-3 Muscle Building Steroids , Muscle Mass
Steroids For Immune Suppressant
1. Quick Details:
Appearance: White powder
Storage: Store in a cool, dry place. Away from the light, heat and
2 . Description:
"Tacrolimus" is a descriptor in the National Library of Medicine's
controlled vocabulary thesaurus, MeSH (Medical Subject Headings).
Descriptors are arranged in a hierarchical structure, which enables
searching at various levels of specificity.A macrolide isolated
from the culture broth of a strain of Streptomyces tsukubaensis
that has strong immunosuppressive activity in vivo and prevents the
activation of T-lymphocytes in response to antigenic or mitogenic
stimulation in vitro.
Tacrolimus (also FK-506 or Fujimycin) is an immunosuppressive drug
whose main use is after organ transplant to reduce the activity of
the patient’s immune system and so the risk of organ rejection. It
is also used in a topical preparation in the treatment of severe
atopic dermatitis, severe refractory uveitis after bone marrow
transplants, and the skin condition vitiligo.
Tacrolimus is chemically known as a macrolide. It reduces
peptidyl-prolyl isomerase activity by binding to the immunophilin
FKBP-12 (FK506 binding protein) creating a new complex. This
FKBP12-FK506 complex interacts with and inhibits calcineurin thus
inhibiting both T-lymphocyte signal transduction and IL-2
3 . Function:
Tacrolimus is used together with other medicines to prevent the
body from rejecting a transplanted organ. This medicine may be used
with steroids, azathioprine, basiliximab, or mycophenolate mofetil.
Tacrolimus belongs to a group of medicines known as
Tacrolimus is a very strong medicine. It can cause side effects
that can be very serious, such as kidney problems. It may also
decrease the body's ability to fight infections. You and your
doctor should talk about the benefits of this medicine as well as
the risks of using it. Tacroz Forte Ointment (Tacrolimus) is used
to treat atopic dermatitis (more commonly known as eczema). It is a
topical medication which is normally prescribed for patients who
have not responded successfully to other eczema medication.
The ointment is a type of topical calcineurin inhibitor (TCIs) that
works by weakening the patient`s immune system, which as a
consequence directly reduces the severity of eczema and its
symptoms. It should not be used by patients who have any kind of
weak immune system.
4 . Muscle Building Steroids: